Introduction

MCQs & Solution

Q1. What does “pharmacokinetics” include?

a) Influence of drugs on metabolism processes

b) Drug biotransformation in the organism

c) Complications of drug therapy

d) Influence of drugs on genes

Ans: b) Drug biotransformation in the organism

  • Pharmacokinetics: ADME are referred as Pharmacokinetics
  • Other options are related to Pharamacodymanic
  • Influence of drugs on metabolism is also a Pharmacodynamic because drug affect the metabolism means it is effect of drug on metabolic process

Q2. Pick out the appropriate alimentary route of administration when passage of drugs through liver is minimized:

a) Oral

b) intraperitonial

c) Rectal

d) Intraduodenal

Ans: c) Rectal

  • Rectal route produces local effect and drug by rectal route absorbs at the site
  • While drug by the other route, which mentioned above, goes to liver for metabolism via portal vein.

Q3. Generic name is accepted by

a) BAN

b) NDA

c) USP

d) USFDA

Ans: a) BAN

  • British Approved Name (BAN) and United State Adopted Name (USAN)
  • These agencies approved the Non-priority/generic name of the pharmaceutical drugs

Q4. Which drug is favored in sublingual route:

a) Nitroglycerine

b) Isoprenaline

c) Desaminooxytocin

d) All

Ans: d) All

  • All drugs are favored in sublingual route because they may destroy by gastric juice.

Q5. Pick out the parenteral route of medicinal agent administration:

a) Rectal

b) Oral

c) Sublingual

d) Inhalation

Ans: d) Inhalation

  • Enteral route means by the GIT, so other three routes are enteral routes while Inhalation is the parenteral route

Q6. Pharmacodynamics involves the following?

a) Information about main mechanisms of drug absorption

b) Information about unwanted effects

c) Information about biological barriers

d) Information about excretion of a drug from the organism

Ans: b) Information about unwanted effects

  • Other 3 option is related to pharmacokinetic properties
  • Don’t confuse in option A, mechanism of absorption process not to drug action

Q7. Which effect may lead to toxic reactions when a drug is taken continuously or repeatedly?

a) Refractoriness

b) Cumulative effect

c) Tolerance

d) Tachyphylaxis

Ans: b) Cumulative effect

  • Repeated administration of drugs caused accumulation in body that is called cumulative effects

Q8. What phenomenon can occur in case of using a combination of drugs?

a) Tolerance

b) Tachyphylaxis

c) Accumulation

d) Synergism

Ans: d) Synergism

  • Synergism, Additive, and Antagonism effect are phenomenon of combination of drugs
  • Synergism effects = >A or B
  • Additive effects = A+B

Q9. If two drugs with the same effect, taken together, produce an effect that is equal in magnitude to the sum of the effects of the drugs given individually, it is called as:

a) Antagonism

b) Potentiation

c) Additive effect

d) None of the above

Ans: c) Additive effect

Additive effect =  A+B

Q10. Which route of drug administration is most likely to lead to the first-pass effect?

a) Sublingual

b) Oral

c) Intravenous

d) Intramuscular

Ans: b) Oral

Q.11. What is characteristic of the oral route?

a) Fast onset of effect

b) Absorption depends on GI tract secretion and motor function

c) A drug reaches the blood passing the liver

d) The sterilization of medicinal forms is obligatory

Ans: b) Absorption depends on GI tract secretion and motor function

 Q12. Parenteral administration:

a) Cannot be used with unconsciousness patients

b) Generally results in a less accurate dosage than oral administration

c) Usually produces a more rapid response than oral administration

d) Is too slow for emergency use

Ans: c) Usually produces a more rapid response than oral administration

Q13. What is characteristic of the intramuscular route of drug administration?

a) Only water solutions can be injected

b) Oily solutions can be injected

c) Opportunity of hypertonic solution injections

d) The action develops slower, than at oral administration

Ans: b) Oily solutions can be injected

 Q14. Correct statements listing characteristics of a particular route of drug administration include all of the following EXCEPT:

a) Intravenous administration provides a rapid response

b) Intramuscular administration requires a sterile technique

c) Inhalation provides slow access to the general circulation

d) Subcutaneous administration may cause local irritation

Ans: c) Inhalation provides slow access to the general circulation

Q15. Atenolol blocks the action of adrenaline by blocking Beta-1 receptor is a example of

a) Competitive Receptor Antagonist

b) Non-Competitive Receptor Agonist

Ans: a) Competitive Receptor Antagonist

Q.16. Histamine constricts the bronchial muscle while adrenaline dilates the bronchial muscle, this type of antagonist is called

a) Receptor Antagonist

b) Chemical Antagonist

c) Physiological Antagonist

d) Physical Antagonist

Ans:     c) Physiological Antagonist

Q17. Which drug is obtained from microbes

a) Aspirin

b) Penicillin

c) Digitoxin

e) Insulin

Ans: b) Penicillin

Q18. Aspirin is a:

a) Non-proprietary name

b) Proprietary name

c) Chemical name

d) None

Ans: Non-proprietary name

Q19. Anxiety, insomnia, and depression is a symptom of

a) Physical dependence

b) Psychological dependence

Ans: b) Psychological dependence