MCQs & Solution
Q1. What does “pharmacokinetics” include?
a) Influence of drugs on metabolism processes
b) Drug biotransformation in the organism
c) Complications of drug therapy
d) Influence of drugs on genes
Ans: b) Drug biotransformation in the organism
- Pharmacokinetics: ADME are referred as Pharmacokinetics
- Other options are related to Pharamacodymanic
- Influence of drugs on metabolism is also a Pharmacodynamic because drug affect the metabolism means it is effect of drug on metabolic process
Q2. Pick out the appropriate alimentary route of administration when passage of drugs through liver is minimized:
a) Oral
b) intraperitonial
c) Rectal
d) Intraduodenal
Ans: c) Rectal
- Rectal route produces local effect and drug by rectal route absorbs at the site
- While drug by the other route, which mentioned above, goes to liver for metabolism via portal vein.
Q3. Generic name is accepted by
a) BAN
b) NDA
c) USP
d) USFDA
Ans: a) BAN
- British Approved Name (BAN) and United State Adopted Name (USAN)
- These agencies approved the Non-priority/generic name of the pharmaceutical drugs
Q4. Which drug is favored in sublingual route:
a) Nitroglycerine
b) Isoprenaline
c) Desaminooxytocin
d) All
Ans: d) All
- All drugs are favored in sublingual route because they may destroy by gastric juice.
Q5. Pick out the parenteral route of medicinal agent administration:
a) Rectal
b) Oral
c) Sublingual
d) Inhalation
Ans: d) Inhalation
- Enteral route means by the GIT, so other three routes are enteral routes while Inhalation is the parenteral route
Q6. Pharmacodynamics involves the following?
a) Information about main mechanisms of drug absorption
b) Information about unwanted effects
c) Information about biological barriers
d) Information about excretion of a drug from the organism
Ans: b) Information about unwanted effects
- Other 3 option is related to pharmacokinetic properties
- Don’t confuse in option A, mechanism of absorption process not to drug action
Q7. Which effect may lead to toxic reactions when a drug is taken continuously or repeatedly?
a) Refractoriness
b) Cumulative effect
c) Tolerance
d) Tachyphylaxis
Ans: b) Cumulative effect
- Repeated administration of drugs caused accumulation in body that is called cumulative effects
Q8. What phenomenon can occur in case of using a combination of drugs?
a) Tolerance
b) Tachyphylaxis
c) Accumulation
d) Synergism
Ans: d) Synergism
- Synergism, Additive, and Antagonism effect are phenomenon of combination of drugs
- Synergism effects = >A or B
- Additive effects = A+B
Q9. If two drugs with the same effect, taken together, produce an effect that is equal in magnitude to the sum of the effects of the drugs given individually, it is called as:
a) Antagonism
b) Potentiation
c) Additive effect
d) None of the above
Ans: c) Additive effect
Additive effect = A+B
Q10. Which route of drug administration is most likely to lead to the first-pass effect?
a) Sublingual
b) Oral
c) Intravenous
d) Intramuscular
Ans: b) Oral
Q.11. What is characteristic of the oral route?
a) Fast onset of effect
b) Absorption depends on GI tract secretion and motor function
c) A drug reaches the blood passing the liver
d) The sterilization of medicinal forms is obligatory
Ans: b) Absorption depends on GI tract secretion and motor function
Q12. Parenteral administration:
a) Cannot be used with unconsciousness patients
b) Generally results in a less accurate dosage than oral administration
c) Usually produces a more rapid response than oral administration
d) Is too slow for emergency use
Ans: c) Usually produces a more rapid response than oral administration
Q13. What is characteristic of the intramuscular route of drug administration?
a) Only water solutions can be injected
b) Oily solutions can be injected
c) Opportunity of hypertonic solution injections
d) The action develops slower, than at oral administration
Ans: b) Oily solutions can be injected
Q14. Correct statements listing characteristics of a particular route of drug administration include all of the following EXCEPT:
a) Intravenous administration provides a rapid response
b) Intramuscular administration requires a sterile technique
c) Inhalation provides slow access to the general circulation
d) Subcutaneous administration may cause local irritation
Ans: c) Inhalation provides slow access to the general circulation
Q15. Atenolol blocks the action of adrenaline by blocking Beta-1 receptor is a example of
a) Competitive Receptor Antagonist
b) Non-Competitive Receptor Agonist
Ans: a) Competitive Receptor Antagonist
Q.16. Histamine constricts the bronchial muscle while adrenaline dilates the bronchial muscle, this type of antagonist is called
a) Receptor Antagonist
b) Chemical Antagonist
c) Physiological Antagonist
d) Physical Antagonist
Ans: c) Physiological Antagonist
Q17. Which drug is obtained from microbes
a) Aspirin
b) Penicillin
c) Digitoxin
e) Insulin
Ans: b) Penicillin
Q18. Aspirin is a:
a) Non-proprietary name
b) Proprietary name
c) Chemical name
d) None
Ans: Non-proprietary name
Q19. Anxiety, insomnia, and depression is a symptom of
a) Physical dependence
b) Psychological dependence
Ans: b) Psychological dependence